R&D Systems™ Recombinant Mouse FGFR3 alpha (IIIb) Fc Chimera Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

The Recombinant Mouse FGF R3 alpha (IIIb) Fc Chimera Protein is derived from NS0. The Recombinant Mouse FGF R3 alpha (IIIb) Fc Chimera Protein has been validated for the following applications: Bioactivity.

Specifications

• Accession Number: NP_001156689
• For Use With (Application): Bioactivity
• Gene ID (Entrez): 2261
• Molecular Weight (g/mol): Observed M.W.: 83-101kDa, reducing conditions, Theoretical M.W.: 63kDa
• Name: FGFR3
• Quantity: 50 μg
• Source: Mouse myeloma cell line,NS0-derived mouse FGF R3 protein, (N-terminus) Mouse FGF R3 (IIIb) (Ala33-Tyr369) Accession &Num; NP_001156689 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU per 1μg of the protein by the LAL method.
• Gene Alias: CD333, CEK, EC 2.7.10, FGF R3, fibroblast growth factor receptor 3, HSFGFR3EX, JTK4, JTK4thanatophoric dwarfism
• Common Name: FGF R3
• Gene Symbol: Fgfr3
• Biological Activity: Measured by its ability to inhibit FGF acidic-dependent proliferation of BaF3 mouse pro-B cells transfected with human FGF R3 (IIIc). The ED50 for this effect is typically 0.2-1.2μg/mL.
• Conjugate: Unconjugated
• Species: Mouse
• Recombinant: Recombinant
• Expression System: Mouse myeloma cell line, NS0-derived Mouse FGF R3 (IIIb) (Ala33-Tyr369) Accession # NP_001156689, N-terminus; IEGRMD; Human IgG1 (Pro100-Lys330), C-terminus
• Purity or Quality Grade: >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining