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R&D Systems™ Recombinant Mouse FGFR3 alpha (IIIb) Fc Chimera Protein

Catalog No. 9089FR050
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90-89F-R050 50 μg
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Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

The Recombinant Mouse FGF R3 alpha (IIIb) Fc Chimera Protein is derived from NS0. The Recombinant Mouse FGF R3 alpha (IIIb) Fc Chimera Protein has been validated for the following applications: Bioactivity.

Specifications

Accession Number NP_001156689
For Use With (Application) Bioactivity
Gene ID (Entrez) 2261
Molecular Weight (g/mol) Observed M.W.: 83-101kDa, reducing conditions, Theoretical M.W.: 63kDa
Name FGFR3
Quantity 50 μg
Source Mouse myeloma cell line,NS0-derived mouse FGF R3 protein, (N-terminus) Mouse FGF R3 (IIIb) (Ala33-Tyr369) Accession &Num; NP_001156689 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
Endotoxin Concentration <0.10 EU per 1μg of the protein by the LAL method.
Gene Alias CD333, CEK, EC 2.7.10, FGF R3, fibroblast growth factor receptor 3, HSFGFR3EX, JTK4, JTK4thanatophoric dwarfism
Common Name FGF R3
Gene Symbol Fgfr3
Biological Activity Measured by its ability to inhibit FGF acidic-dependent proliferation of BaF3 mouse pro-B cells transfected with human FGF R3 (IIIc). The ED50 for this effect is typically 0.2-1.2μg/mL.
Conjugate Unconjugated
Species Mouse
Recombinant Recombinant
Expression System Mouse myeloma cell line, NS0-derived Mouse FGF R3 (IIIb) (Ala33-Tyr369) Accession # NP_001156689, N-terminus; IEGRMD; Human IgG1 (Pro100-Lys330), C-terminus
Purity or Quality Grade >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining
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