R&D Systems™ Recombinant Mouse Integrin alpha 4 beta 7 Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

The Recombinant Mouse Integrin alpha 4 beta 7 Protein is derived from CHO. The Recombinant Mouse Integrin alpha 4 beta 7 Protein has been validated for the following applications: Bioactivity.

Specifications

• For Use With (Application): Bioactivity
• Gene ID (Entrez): 3676
• Molecular Weight (g/mol): Observed M.W.: 115 - 170kDa, reducing conditions, Theoretical M.W.: 113kDa (Integrin alpha 4), 84kDa (Integrin beta 7)
• Quantity: 50 μg
• Source: Chinese Hamster Ovary cell line,CHO-derived mouse Integrin alpha 4 beta 7/LPAM-1 protein, (N-terminus) Mouse Integrin alpha 4 Tyr34-Gln970 (Arg591Leu) Accession &Num; AAH68313 GS Linker Acidic Tail HHHHHH Mouse Integrin ss7 Glu20-Arg724 Accession &Num; P26011 GS Linker Basic Tail (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70° C as supplied. 1 month, 2 to 8° C under sterile conditions after reconstitution. 3 months, -20 to -70° C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU per 1μg of the protein by the LAL method.
• Gene Alias: 269C wild type, CD49 antigen-like family member D, CD49d, CD49d antigen, CD49d/beta7, CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor, IA4, integrin alpha 4, integrin alpha-4, integrin alpha-4 subunit, Integrin alpha-IV, integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor), LPAM1, LPAM-1, MGC90518, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 subunit alpha
• Common Name: Integrin alpha 4 beta 7/LPAM-1
• Gene Symbol: Itga5
• Biological Activity: Measured by the ability of the immobilized protein to support the adhesion of CHO Chinese hamster ovary cells transfected with VCAM-1. The ED50 for this effect is typically 0.6-3.6μg/mL.
• Conjugate: Unconjugated
• Species: Mouse
• Recombinant: Recombinant
• Expression System: Chinese Hamster Ovary cell line, CHO-derived Mouse Integrin alpha 4 Tyr34-Gln970 (Arg591Leu) Accession # AAH68313, GS Linker, Acidic Tail, N-terminus; HHHHHH; Mouse Integrin ss7 Glu20-Arg724 Accession # P26011, GS Linker Basic Tail, C-terminus
• Purity or Quality Grade: >95%, by SDS-PAGE with Silver Staining