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R&D Systems™ Recombinant Mouse Integrin alpha V beta 8 Protein

Catalog No. 8314AV050
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50 μg
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83-14A-V050 50 μg
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Catalog No. 83-14A-V050 Supplier R&D Systems™ Supplier No. 8314AV050
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Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its binding ability in a functional ELISA. Immobilized Recombinant Mouse Integrin alpha V beta 8 at 2 μg/mL can bind Recombinant Human LAP (TGF-beta 1) (Catalog # 246-LP ) with an apparent Kd <0.1 nM.

Specifications

Accession Number P43406 & Q0VBD0
For Use With (Application) Bioactivity
Formulation Lyophilized from a 0.2 μm filtered solution in PBS and Trehalose.
Gene ID (Entrez) 3685
Molecular Weight (g/mol) M.W. (Observed): 95 - 170 kDa, reducing conditions; M.W. (theoretical): 115 kDa (alpha V subunit), 78 kDa (beta 8 subunit)
Name Integrin alpha V beta 8
Preparation Method Reconstitute at 500μg/mL in sterile PBS.
Quality Control Testing SDS-PAGE: 95 - 170kDa, reducing conditions
Quantity 50 μg
Source Chinese Hamster Ovary cell line, CHO-derived mouse Integrin alpha V beta 8 protein Mouse Integrin aV (Phe31-Val988) (N-terminus) Accession # P43406 His-Pro GGGSGGGS Acidic Tail 6-His tag Mouse Integrin ss8 (Glu43-Ser679) (N-terminus) Accession # Q0VBD0 His-Pro GGGSGGGS Basic Tail (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
Regulatory Status RUO
Termination Phe31 (αV subunit) & Glu43 (β8 subunit)
Without Additives Carrier Protein
Structural Form Noncovalent heterodimer
Endotoxin Concentration <0.10 EU / 1 μg of the protein by the LAL method.
Conjugate Unconjugated
Recombinant Recombinant
Reconstitution Reconstitute at 500 μg/mL in sterile PBS.
Purity or Quality Grade >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
Protein Integrin alpha V beta 8
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