R&D Systems™ Recombinant Mouse Siglec-15 Fc Chimera Protein

Catalog No.	Quantity
10-101-SL050	50 μg

Catalog No. 10-101-SL050 Supplier R&D Systems™ Supplier No. 10101SL050

Description

Measured by its ability to inhibit IL-2 secretion by mouse T cells in the presence of anti-CD3.

Measured by its ability to inhibit IL-2 secretion by mouse T cells in the presence of anti-CD3. The ED50 for this effect is 1-6 μg/mL.

Specifications

• Accession Number: NP_001094508.1
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Gene ID (Entrez): 284266
• Molecular Weight (g/mol): M.W. (Observed): 57-64 kDa; M.W. (theoretical): 52 kDa
• Quantity: 50 μg
• Source: Mouse myeloma cell line, NS0-derived mouse Siglec-15 protein Mouse Siglec-15 (Arg24-Tyr250) (N-terminus) Accession # NP_001094508.1 IEGRMDP Mouse IgG2a (Glu98-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Conjugate: Unconjugated
• Species: Mouse
• Reconstitution: Reconstitute at 200 μg/mL in PBS.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose
• Purity or Quality Grade: >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: Siglec-15