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R&D Systems™ Recombinant Mouse TIGIT Fc Chimera Protein

Catalog No. 7267TG01M
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72-67T-G01M 1 mg
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Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its binding ability in a functional ELISA. When Recombinant Mouse CD155/PVR (Catalog # 6909-CD ) is coated at 2.5 μg/mL (100 μL/well), the concentration of Recombinant Mouse TIGIT Fc Chimera that produces 50% optimal binding response is 10-50 ng/mL.

Specifications

Accession Number NP_001139797
Characterization Bioactivity
For Use With (Application) Bioactivity
Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Gene ID (Entrez) 201633
Molecular Weight (g/mol) M.W. (Observed): 50-60 kDa, reducing conditions; M.W. (theoretical): 40.1 kDa (monomer)
Quantity 1 mg
Source Mouse myeloma cell line, NS0-derived mouse TIGIT protein Mouse TIGIT (Gly26-Thr143) (N-terminus) Accession # NP_001139797 IEGRMDP Mouse IgG2A (Glu98-Lys330) (C-terminus)
Storage Requirements Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
Endotoxin Concentration <0.10 EU / 1 μg of the protein by the LAL method.
Gene Symbol Tigit
Product Type Recombinant Protein
Conjugate Unconjugated
Species Mouse
Reconstitution Reconstitute at 100 μg/mL in PBS.
Purity or Quality Grade >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
Protein TIGIT
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