R&D Systems™ Recombinant Mouse TIM-1/KIM-1/HAVCR Isoform A Fc Protein

Catalog No.	Quantity
10699TM050	50 μg

Catalog No. 10699TM050 Supplier R&D Systems™ Supplier No. 10699TM050

Description

Recombinant Protein

Measured in a cell proliferation assay using PHA-stimulated human T lymphoblasts. The ED50 for this effect is 0.5-4.0 μg/mL.. Measured by its binding ability in a functional ELISA. When Recombinant Mouse TIM-1/KIM-1/HAVCR Isoform A Fc Chimera (Catalog # 10699-TM) is immobilized at 1 μg/mL (100 μL/well), Recombinant Mouse TIM-4 (Catalog # 2826-TI ) binds with an ED50 of 0.8-6.4 μg/mL.

Specifications

• Accession Number: NP_599009.2
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 26762
• Molecular Weight (g/mol): M.W.-observed: 75-85 kDa, under reducing conditions, M.W.-theroretical: 50 kDa
• Quantity: 50 μg
• Source: Mouse myeloma cell line, NS0-derived mouse TIM-1/KIM-1/HAVCR protein Mouse TIM-1/KIM-1/HAVCR (Tyr22-Gly237) (N-terminus) Accession # NP_599009.2 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Alias: CD365, HAVCR1, HAVCR-1, HAVCRT cell immunoglobin domain and mucin domain protein 1, hepatitis A virus cellular receptor 1, Kidney injury molecule 1, KIM1, KIM-1, T-cell immunoglobulin and mucin domain-containing protein 1, TIM1, TIM-1 TIM, TIM1TIMD-1, TIMD1T-cell membrane protein 1
• Conjugate: Unconjugated
• Reconstitution: Reconstitute at 500 μg/mL in PBS.
• Purity or Quality Grade: >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: TIM-1/KIM-1/HAVCR