R&D Systems™ Recombinant Mouse VSIG1 Fc Chimera Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its ability to inhibit anti-CD3 antibody induced IL-17 secretion by human peripheral blood mononuclear cells (PBMC). The ED50 for this effect is 1-6 μg/mL.

Specifications

• Accession Number: NP_084457
• Characterization: Bioactivity
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 340547
• Molecular Weight (g/mol): M.W. (Observed): 63-76 kDa, reducing conditions; M.W. (theoretical): 50 kDa
• Quantity: 50 μg
• Source: Mouse myeloma cell line, NS0-derived mouse VSIG1 protein Mouse VSIG1 (Val23-Glu234) (N-terminus) Accession # NP_084457 IEGRMDP Mouse IgG2a (Glu98-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Alias: Cell surface A33 antigen, dJ889N15.1, Glycoprotein A34, GPA34,mgC44287,1700062D20Rik, V-set and immunoglobulin domain containing 1, V-set and immunoglobulin domain-containing protein 1
• Product Type: Recombinant Protein
• Conjugate: Unconjugated
• Species: Mouse
• Reconstitution: Reconstitute at 200 μg/mL in PBS.
• Purity or Quality Grade: >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie™ Blue Staining.
• Protein: VSIG1