R&D Systems™ Recombinant Rat 4-1BB/TNFRSF9 Fc Chimera Protein

Catalog No.
79684B050	50ug; Carrier Free

Catalog No. 79684B050 Supplier R&D Systems™ Supplier No. 79684B050

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its binding ability in a functional ELISA. When Recombinant Rat 4-1BB/TNFRSF9/CD137 Fc Chimera is present at 100 ng/mL, the concentration of Recombinant Mouse 4-1BB Ligand/TNFSF9 (Catalog # 1246-4L ) that produces 50% of the optimal binding response is approximately 5-25 ng/mL.

Specifications

• Accession Number: NP_001020944
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS.
• Gene ID (Entrez): 3604
• Molecular Weight (g/mol): M.W. (Observed): 60-65 kDa, reducing conditions; M.W. (theoretical): 44.9 kDa (monomer)
• Quantity: 50 μg
• Source: Mouse myeloma cell line, NS0-derived rat 4-1 BB/TNFRSF9/CD137 protein Rat 4-1 BB (Thr24-Val188) (N-terminus) Accession # NP_001020944 IEGRMDP Mouse IgG2A (Glu98-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Structural Form: Disulfide-linked homodimer
• Endotoxin Concentration: <0.01 EU / 1 μg of the protein by the LAL method.
• Gene Symbol: Tnfrsf9
• Product Type: 4-1BB/TNFRSF9/CD137 Fc Chimera
• Conjugate: Unconjugated
• Species: Rat
• Recombinant: Recombinant
• Reconstitution: Reconstitute at 100 μg/mL in PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain
• Protein: 4-1 BB/TNFRSF9/CD137