R&D Systems™ Recombinant Rat CD40/TNFRSF5 Fc Chimera Protein

Description

Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility.

Measured by its ability to inhibit CD40 Ligand-induced proliferation of mouse B cells. The ED50 for this effect is 0.1-0.6 μg/mL.

Specifications

• Accession Number: Q4QQW2
• For Use With (Application): Bioactivity
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS and Trehalose.
• Gene ID (Entrez): 958
• Molecular Weight (g/mol): M.W. (Observed): 57-63 kDa, reducing conditions; M.W. (theoretical): 46 kDa (monomer)
• Name: CD40/TNFRSF5 Fc Chimera
• Preparation Method: Reconstitute at 200μg/mL in sterile PBS.
• Quality Control Testing: SDS-PAGE: 57-63kDa, reducing conditions
• Quantity: 50 μg
• Source: Mouse myeloma cell line, NS0-derived rat CD40/TNFRSF5 protein Rat CD40 (Val24-Arg193) (N-terminus) Accession # Q4QQW2 IEGRMDP Mouse IgG2A (Glu98-Lys330) (C-terminus)
• Storage Requirements: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution.
• Regulatory Status: RUO
• Termination: Val24
• Without Additives: Carrier Protein
• Structural Form: Disulfide-linked homodimer
• Endotoxin Concentration: <0.10 EU / 1 μg of the protein by the LAL method.
• Gene Symbol: Cd40
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Reconstitution: Reconstitute at 200 μg/mL in sterile PBS.
• Purity or Quality Grade: >95%, by SDS-PAGE with silver staining.
• Protein: CD40/TNFRSF5