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Invitrogen™ RED Polyclonal Antibody
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Catalog No. PIPA583926
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100 μL
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PIPA583926 100 μL
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Catalog No. PIPA583926 Supplier Invitrogen™ Supplier No. PA583926
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DMAVDSDEEV DYSKMDQGNK KGPLGRWDFD TQEEYSEYMN NKEALPKAAF QYGIKMSEGR KTRRFKETND KAELDRQWKK ISAIIEKRKK MEADGVEVKR PK Highest antigen sequence indentity to the following orthologs: Rat - 100%, Mouse - 99%.

Insulin-like growth factor-II messenger RNA (mRNA)-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family and is expressed during embryogenesis and in some malignancies. IMP-3 is expressed in malignant melanoma but not in benign nevi, even when dysplastic features are present; IMP-3 is expressed in a significantly higher proportion of melanomas than Spitz nevi; and IMP-3 is expressed in metastatic melanomas significantly more than in thin melanomas. IMP-3 appears to be involved in the progression of malignant melanoma and may play an important role in the regulation of the biologic behavior of this tumor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RED
Applications Immunohistochemistry (Paraffin), Immunocytochemistry, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene IK
Gene Accession No. Q13123
Gene Alias arginine/glutamic acid/aspartic acid repeat containing protein; chondrosarcoma-associated protein 2; CSA2; Cytokine IK; Cytokine IK factor; IK; IK cytokine; IK cytokine, down-regulator of HLA II; IK factor; MuRED; prer protein; protein Red; Protein RER; RD element; RED; Rer
Gene Symbols IK
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human IK. Recombinant protein control fragment (Product #RP-103036).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3550
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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