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Invitrogen™ REPIN1 Polyclonal Antibody
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Catalog No. PIPA531367
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100 μL
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PIPA531367 100 μL
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Catalog No. PIPA531367 Supplier Invitrogen™ Supplier No. PA531367
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HeLa. Predicted reactivity: Mouse (96%), Rat (97%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Replication initiator 1 (REPIN1) is a gene encoding a zinc-finger protein that plays a critical role in various metabolic processes. Located on chromosome 7 in humans, REPIN1 is prominently expressed in liver and adipose tissues. It is associated with the regulation of body weight and triglyceride levels, as evidenced by its locus within a quantitative trait locus (QTL) related to these metabolic traits. The REPIN1 protein is involved in enhancing DNA bending, which is crucial for replication initiation. Studies have shown that deleting REPIN1 in the liver can lead to improved insulin sensitivity and altered lipid metabolism, with secondary effects on adipose tissue. Additionally, REPIN1 is implicated in iron metabolism and apoptosis regulation, further underscoring its multifaceted role in cellular processes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen REPIN1
Applications Western Blot
Classification Polyclonal
Concentration 0.74 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene REPIN1
Gene Accession No. Q9BWE0
Gene Alias 60 kDa origin-specific DNA-binding protein; 60 kDa replication initiation region protein; AP4; ATT-binding protein; DHFR oribeta-binding protein RIP60; H_DJ0584D14.12; REPIN1; replication initiation region protein (60kD); replication initiator 1; RIP60; Zfp464; Zinc finger protein 464; zinc finger protein 464 (RIP60); zinc finger protein AP4; ZNF464
Gene Symbols REPIN1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human REPIN1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 29803
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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