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REST Polyclonal Antibody, Bethyl Laboratories

Catalog No. p-7140259
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50-155-7869 20 μL
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Catalog No. 50-155-7869 Supplier Bethyl Laboratories, Inc Supplier No. A300540AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.

Specifications

Antigen REST
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene REST
Gene Accession No. Q13127
Gene Alias NRSF, XBR, X2 box repressor; neural-restrictive silencer factor; neuron restrictive silencer factor; repressor binding to the X2 box
Gene Symbols REST
Host Species Rabbit
Immunogen Between 1050 and C-term
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5978
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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