Invitrogen™ RFC2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA528189

Catalog No. PIPA528189

Description

Recommended positive controls: 293T, A431, HeLa, HepG2, H1299. Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (87%), Xenopus laevis (91%), Chicken (94%), Rhesus Monkey (99%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene has been defined on chromosome 2.

Specifications

• Antigen: RFC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RFC2
• Gene Alias: 2610008M13Rik; 40kDa; A1 40 kDa subunit; Activator 1 40 kDa subunit; activator 1 subunit 2; Activator 1 subunit C2; AI326953; MGC3665; Recc2; replication factor C (activator 1) 2; replication factor C (activator 1) 2, 40kDa; replication factor C 40 kDa subunit; Replication factor C subunit 2; replication factor C, 40 kDa; RF-C 40 kDa subunit; RFC2; RFC40
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5982
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.43 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P35250
• Gene Symbols: RFC2
• Immunogen: Recombinant fragment corresponding to a region within amino acids 91 and 354 of Human RFC2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG