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Invitrogen™ RGS1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA529579
Description
Recommended positive controls: K562. Predicted reactivity: Mouse (86%), Rhesus Monkey (97%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the regulator of G-protein signaling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
Specifications
RGS1 | |
Polyclonal | |
Unconjugated | |
RGS1 | |
1R20; B-cell activation protein BL34; BL34; Early response protein 1R20; epididymis secretory protein Li 87; HEL-S-87; IER1; immediate-early response 1, B-cell specific; IR20; Regulator of G-protein signaling 1; regulator of G-protein signalling 1; RGS1 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
5996 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
0.57 mg/mL | |
PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
Q08116 | |
RGS1 | |
Recombinant fragment corresponding to a region within amino acids 1 and 209 of Human RGS1. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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