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Invitrogen™ RGS18 Polyclonal Antibody
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Catalog No. PIPA583792
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PIPA583792 100 μL
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Catalog No. PIPA583792 Supplier Invitrogen™ Supplier No. PA583792
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Rabbit Polyclonal Antibody

Immunogen sequence: LFFSQINMCE SKEKTFFKLI HGSGKEETSK EAKIRAKEKR NRLSLLVQKP EFHEDTRSSR SGHLAKETRV SPEEAVKWGE S Highest antigen sequence indentity to the following orthologs: Rat - 78%, Mouse - 83%.

This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RGS18
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene RGS18
Gene Accession No. Q9NS28
Gene Alias regulator of G-protein signaling 18; regulator of G-protein signalling 13; regulator of G-protein signalling 18; RGS13; RGS18; RP11-142L4.1
Gene Symbols RGS18
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RGS18. Recombinant protein control fragment (Product #RP-94313).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64407
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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