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Invitrogen™ RhoBTB1/RhoBTB2 Polyclonal Antibody
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Catalog No. PIPA536326
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PIPA536326 100 μL
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Catalog No. PIPA536326 Supplier Invitrogen™ Supplier No. PA536326
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 83 kDa. Purity is >95% by SDS-PAGE.

RHOBTB1 (Rho-related BTB domain-containing protein 1) and RHOBTB3 (Rho-related BTB domain-containing protein 3) each contain two BTB (POZ) domains and belong to the RhoBTB subfamily of Rho GTPases. Members of the RhoBTB subfamily are evolutionarily conserved and are characterized by a proline-rich region, a GTPase domain and two tandem BTB repeats. While both RHOBTB1 and RHOBTB3 are expressed ubiquitously, RHOBTB1 is found at high levels in placenta, stomach, testis, kidney and skeletal muscle, whereas RHOBTB3 is found at high levels in neural and cardiac tissues. RHOBTB1 is thought to play a role in GTPase-mediated signaling and may participate in organization of the Actin filament system. Additionally, RHOBTB1 expression is decreased in head and neck carcinomas, suggesting a possible role for RHOBTB1 as a tumor suppressor.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RhoBTB1/RhoBTB2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene RHOBTB1
Gene Accession No. O94844, Q91V93, Q9BYZ6, Q9DAK3
Gene Alias 1700008H16Rik; 3110048G13Rik; AI173445; AI573858; AV350930; DBC2; deleted in breast cancer 2 gene protein; Deleted in breast cancer 2 gene protein homolog; E130206H14Rik; KIAA0717; KIAA0740; mKIAA0717; p83; Rho related BTB domain containing 1; Rho related BTB domain containing 2; Rhobtb1; Rhobtb2; Rho-related BTB domain containing 1; Rho-related BTB domain containing 2; rho-related BTB domain-containing protein 1; Rho-related BTB domain-containing protein 2
Gene Symbols RHOBTB1, RHOBTB2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 52-98 of human RhoBTB1.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23221, 246710, 306004, 309722, 69288, 9886
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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