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Cayman Chemical RhodojaponIn III 25mg

Supplier: Cayman Chemical 3634525 MG

An inhibitor of H-PGDS (IC50 55 8 nM) selective for H-PGDS over L-PGDS at 100 UM as well as over enzyme and receptor panels at 10 UM inhibits A23187-induced PGD2 production in KU812 and RBL-2H3 basophils (IC50s 78 3 and 181 3 nM respectively) inhibits ovalbumin-induced nasal lavage fluid eosinophil infiltration and late-phase nasal obstruction in an ovalbumin-sensitized guinea pig model of allergic rhinitis at 30 mg/kg
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