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Invitrogen™ Rhodopsin Monoclonal Antibody (4D2), FITC
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Catalog No. PIMA545245 Shop All Thermo Scientific Products
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100 μg
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PIMA545245 100 μg
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Catalog No. PIMA545245 Supplier Invitrogen™ Supplier No. MA545245
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Description

Mouse Monoclonal Antibody

1 μg/mL of MA5-45245 was sufficient for detection of rhodopsin in 10 μg of rat eye lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 40kDa. Binds specifically to the N-terminus of Rhodopsin. Does not detect Rhodopsin in invertebrates.

Visual pigments such as rhodopsin and porphyropsin are light-absorbing molecules that mediate vision. Rhodopsin consists of an apoprotein, opsin, covalently linked to 11-cis-retinal. This receptor is coupled to the activation of phospholipase C. Porphyropsin consists of opsin covalently linked to 11-cis 3,4-didehydroretinal.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Rhodopsin
Applications Immunocytochemistry, Immunohistochemistry, Western Blot, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 4D2
Concentration 1 mg/mL
Conjugate FITC
Formulation PBS, 9.09mM sodium bicarbonate with 136.36mM ethanolamine, 640.91mM DMSO and no preservative; pH 7.4
Gene RHO
Gene Accession No. P02699, P08100, P15409
Gene Alias CSNBAD1; L opsin; Long Wavelength Sensitive opsin; LWS opsin; MGC138309; MGC138311; Noerg1; OPN 2; Opn2; Ops; opsin 2; opsin 2, rod pigment; opsin-2; Red Opsin; retinal rod opsin pigment rh1.1; Rh; RH1; rh1.1; rho; rho protein; rhodopsin; rhodopsin (opsin 2, rod pigment) (retinitis pigmentosa 4, autosomal dominant); Rhodopsin (retinitis pigmentosa 4, autosomal dominant); rhodopsin-like-1.1 rod opsin; Rod Opsin; RP 4; RP4; seven transmembrane light receptor; unknown opsin-like protein; wu:fi06d11; zfo2; zfrho
Gene Symbols RHO
Host Species Mouse
Immunogen Bovine Rhodopsin.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 103176745, 212541, 509933, 6010
Target Species Amphibian, Avian, Bovine, Fish, Human, Mouse, Shark
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG2b κ
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