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Invitrogen™ RhoH Polyclonal Antibody
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Catalog No. PIPA556443
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PIPA556443 100 μL
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Catalog No. PIPA556443 Supplier Invitrogen™ Supplier No. PA556443
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Rabbit Polyclonal Antibody

Immunogen sequence: KWIGEIRSNL PCTPVLVVAT QTDQREMGPH RASCVNAMEG KKLAQDVRAK GYLECSALSN RGVQQVFECA VRTAVNQARR RNRRRLFSIN ECKI Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.

The Rho subfamily of small GTP-binding proteins mediates many fundamental cellular functions. The commonly studied members (Rho, Rac, and CDC42) regulate actin reorganization and affect diverse cellular responses, including adhesion, cytokinesis, and motility. RhoH, also known as TTF (Translocation Three Four), Rho-related GTP-binding protein and ras homolog gene family member H, is unlike most other small G proteins. Most small G proteins are expressed ubiquitously, however, Rho H is expressed only in hemopoietic cells and tissues. Translocations and a high frequency of Rho H mutation have been detected in primary lymphoma cells. Rho H expression has also been observed in activated neutrophils. RhoH is GTPase deficient, remaining in a GTP-bound activated state without cycling. Rho H may be involved in the functional differentiation of T cells and in cytoskeleton organization. The RhoH/TTF (ARHH) gene maps to chromosome 4p13 and encodes a 191 -amino acid polypeptide.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RhoH
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene RHOH
Gene Accession No. Q15669
Gene Alias 5830400A04Rik; ARHH; AU019774; GTP-binding protein TTF; ras homolog family member H; ras homolog gene family, member H; RHOH; rho-related GTP-binding protein RhoH; Translocation three four protein; TTF; TTF, translocation three four
Gene Symbols RHOH
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RhoH. Recombinant protein control fragment (Product #RP-95490).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 399
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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