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Tocris Bioscience™ Ribociclib
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Catalog No. 705050
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Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Dual cdk4/cdk6 inhibitor; orally bioavailable

Ribociclib is a dual cdk4/cdk6 inhibitor. Induces G1 phase cell cycle arrest and senescence in neuroblastoma cell lines (IC50 = 306 nM). Delays tumor growth in vivo. Orally bioavailable.

Specifications

Chemical Name or Material 7-Cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
CAS 1211441-98-3
Quantity 50 mg
Molecular Formula C23H30N8O
Purity 98%
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