Thermo Scientific Chemicals Rifampin, Molecular Biology Reagent

Description

Rifampin (rifampicin), CAS # 13292-46-1, is a synthetic rifamycin antibiotic that works by inhibiting RNA and DNA synthesis and exhibits activity against the tuberculosis microbe. | CAS: 13292-46-1 | C43H58N4O12 | 822.953 g/mol

Antibiotic effective against mycobacteria. Can also inhibit DNA polymeraseRifampin is an antibiotic used in the treatment of tuberculosis and its related microbacterial infections. It is involved in the inhibition of DNA polymerase and RNA polymerase. As an antipruritic agent, it is used in the autoimmune cholestatic liver disease and primary biliary cirrhosis (PBC).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Rifampin is a rifamycin class antibiotic synthesized to resemble the compound isolated from Amycolatopsis rifamycinica

Applications

• Rifampin can be used as a bacteriostatic that prevents RNA and DNA synthesis, particularly in mycobacteria
• It may also act as an antineoplastic, a neuroprotective, and inhibitor of angiogenesis

Specifications

Chemical Identifiers

• CAS: 13292-46-1
• Molecular Formula: C43H58N4O12
• Molecular Weight (g/mol): 822.953
• MDL Number: MFCD00151389
• InChI Key: FZYOVNIOYYPUPY-HRJPTAQKSA-N
• Synonym: Rifampicin
• PubChem CID: 131839595
• SMILES: CC1C=CC=C(C(=O)NC2=C(C3=C(C(=C4C(=C3C(=O)C2=CNN5CCN(CC5)C)C(=O)C(O4)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)C

• Type: Rifampicin
• Physical Form: Powder
• Melting Point: 183°C to 188°C
• Color: Brown/Red to Orange
• Quantity: 1 g
• Beilstein: 5723476
• Merck Index: 14,8216
• Solubility Information: Soluble in DMSO or methanolSoluble in water,ethyl acetate,chloroform,methanol,tetrahydrofuran and dimethyl sulfoxide.
• Formula Weight: 822.94
• Grade: Molecular Biology
• Chemical Name or Material: Rifampin

Safety and Handling

Hazard Category	H302-H315-H319-H335
Hazard Statement	GHS H Statement H302-H315-H319-H335 Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
EINECSNumber	236-312-0
RTECSNumber	VJ7000000
TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only