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Rifamycin SV Sodium Salt, MP Biomedicals™

Catalog No. MP021915162 Shop All MP Biomedicals, Inc Products
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MP021915162 250 mg
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Catalog No. MP021915162 Supplier MP Biomedicals, Inc Supplier No. 02191516.2
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Description

Used to study potential genes that may be involved in the conversion of rifamycin SV into rifamycin B. Rifamycin SV Sodium Salt, MP Biomedicals is a broad-spectrum semisynthetic antimicrobial agent of the rifamycin group. It has limited oral absorption.

Rifamycin SV inhibits selective (E. coli, B. subtilis) bacterial DNA-dependent RNA polymerase by binding to the polymerase β-subunit, a mechanism similar to rifabutin. It acts as a selective cytochrome P450 3A4 inducer. It has limited oral absorption. It is active against Gram-positive bacteria and is moderately active against Gram-negative organisms.

  • Used to study potential genes, such as rif15 and rif16, which may be involved in the conversion of rifamycin SV into rifamycin B
  • Potential treatment for traveler’s diarrhea (TD), Clostridium difficile-associated disease (CDAD) and rheumatoid knee synovitis
  • It is used in electron spin resonance studies
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 14897-39-3
Molecular Formula C37H47NNaO12
Molecular Weight (g/mol) 720.77
MDL Number MFCD09752825
InChI Key YVOFSHPIJOYKSH-DITFEXNXSA-N
Synonym rifamycin sodium salt, rifamycin sodium usan, rifamycin sv sodium salt, rifocina tn, otofa tn
PubChem CID 124219641
IUPAC Name sodium (7S,9Z,11S,12R,13S,14R,15R,16R,17S,18S,19Z,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1⁴,⁷.0⁵,²⁸]triaconta-1,3,5(28),9,19,21,25(29),26-octaen-13-yl acetate
SMILES [Na+].CO[C@H]1\C=C/O[C@@]2(C)OC3=C(C)C(O)=C4C(O)=C(NC(=O)\C(C)=C/C=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)C=C(O)C4=C3C2=O

Specifications

Quantity 250 mg
Solubility Information Ethanol: soluble (50mg/mL)
Formula Weight 719.8
Physical Form Powder

Safety and Handling

Recommended Storage +4°C. Store under nitrogen. Protect from light.
WARNING: Cancer - www.P65Warnings.ca.gov
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