RIMS3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-9968	150 μL

Catalog No. 50-172-9968 Supplier Proteintech Group Inc Supplier No. 150881AP150UL

Description

Rabbit Polyclonal Antibody

Rab3-interacting molecules (RIMs) are synaptic proteins are synaptic proteins necessary for neural transmission and plasticity. While both Rim1 and Rim 2 are thought to be effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known of Rim3. Expression of Rim3 in PC12 cells induced a significant increase in calcium-triggered exocytosis, with no appreciable change in the baseline release, suggesting that it plays a role in the regulation of exocytosis. Rim3 protein localizes primarily to neuronal dendrites and the postsynaptic densities, as opposed to Rim1 which is found in presynapse locations, indicating that Rim3 may contribute to synapse transmission and plasticity.

Specifications

• Antigen: RIMS3
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.17 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: RIMS3
• Gene Accession No.: Q80U57, Q9JIR3, Q9UJD0
• Gene Alias: KIAA0237, NIM3, Rab 3 interacting molecule 3, RIM 3, RIM3, RIM3 gamma, RIMS3
• Gene Symbols: Rims3
• Host Species: Rabbit
• Immunogen: RIMS3 Fusion Protein Ag7171
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 242662, 65025, 9783
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG