Invitrogen™ RING1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527476

Catalog No. PIPA527476

Description

Recommended positive controls: 293T. Predicted reactivity: Mouse (98%), Rat (99%), Xenopus laevis (91%), Dog (99%), Pig (99%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.

Specifications

• Antigen: RING1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RING1
• Gene Alias: E3 ubiquitin-protein ligase RING1; Polycomb complex protein RING1; really interesting new gene 1 protein; RING finger protein 1; RING1; Ring1A; RING-type E3 ubiquitin transferase RING1; Rnf1; Transcription repressor Ring1A
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6015
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q06587
• Gene Symbols: RING1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 200 of Human RING1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG