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Invitrogen™ RING1 Polyclonal Antibody
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Catalog No. PIPA527476
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PIPA527476 100 μL
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Catalog No. PIPA527476 Supplier Invitrogen™ Supplier No. PA527476
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Rabbit Polyclonal Antibody

Recommended positive controls: 293T. Predicted reactivity: Mouse (98%), Rat (99%), Xenopus laevis (91%), Dog (99%), Pig (99%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RING1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene RING1
Gene Accession No. Q06587
Gene Alias E3 ubiquitin-protein ligase RING1; Polycomb complex protein RING1; really interesting new gene 1 protein; RING finger protein 1; RING1; Ring1A; RING-type E3 ubiquitin transferase RING1; Rnf1; Transcription repressor Ring1A
Gene Symbols RING1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human RING1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6015
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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