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Tocris Bioscience™ RITA
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Catalog No. 244310
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10 mg
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Catalog No. Quantity
24-431-0 10 mg
24-431 1 mg
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Catalog No. 24-431-0 Supplier Tocris Bioscience™ Supplier No. 2443/10
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Description

MDM2-p53 interaction inhibitor

Anti-tumor agent that binds wild-type p53 (Kd = 1.5 nM) preventing p53-MDM2 (HDM2) interaction. Induces p53 accumulation and stimulates apoptosis in tumor cell lines expressing wild-type p53 in vitro and in vivo. Inhibits HPV-E6-mediated proteasomal degradation. Suppresses expression of cervical carcinoma HeLa xenografts in vivo.

Chemical Identifiers

CAS 213261-59-7
Molecular Formula C14H12O3S2

Specifications

Quantity 10 mg
Formula Weight 292.37
Purity >97%
Molecular Weight (g/mol) 292.367
Chemical Name or Material RITA

Safety and Handling

Recommended Storage Store at -20°C
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