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Tocris Bioscience™ RKI 1447 dihydrochloride
Potent and selective ROCK inhibitor; antitumor
Supplier: Tocris Bioscience™ 5061/50
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Description
RKI 1447 dihydrochloride is a potent and selective ROCK inhibitor (IC50 values are 6.2 and 14.5 nM for ROCK2 and ROCK1 respectively); suppresses phosphorylation of ROCK substrates MLC-2 and MYPT-1 in human cancer cells, but has no effect on the phosphorylation levels of Akt, MEK, and S6 kinase. Displays anti-invasive and antitumor activities in breast cancer cells.Specifications
>99% | |
50 mg | |
399.29 |
1782109-09-4 | |
RKI 1447 dihydrochloride | |
RKI 1447 dihydrochloride |
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Product Title
For Research Use Only