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RNASE4 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987352
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50-198-7352 100 μL
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Catalog No. 50-198-7352 Supplier Bioss Supplier No. BS6583R
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Rabbit Polyclonal Antibody

RNase 4 and RNase 5/ang 1 are unique among the RNase A ribonuclease genes in that they maintain a complex gene locus that is conserved across species with transcription initiated from tissue-specific dual promoters followed by differential exon splicing. Rnase4 (ribonuclease, RNase A family 4) gene can produce 2 transcripts both encoding 148 amino acid proteins. Rnase 4 is a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. RNase 4 prefers poly(C) as a substrate and hydrolyzes 2′,3′-cyclic nucleotides, with a pH optimum near 8.0. mRNA encoding RNase 4 is detectable in human pancreas, lung, skeletal muscle, heart, kidney and placenta; liver represents the most abundant source.

Specifications

Antigen RNASE4
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene RNASE4
Gene Accession No. P34096
Gene Alias C730049F20Rik; RAB1; Ribonuclease 4; ribonuclease A B1; ribonuclease A family member 4; ribonuclease, RNase A family 4; ribonuclease, RNase A family, 4; RL3; RNase 4; RNASE4; RNS4
Gene Symbols RNASE4
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human RNASE4.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6038
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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