Invitrogen™ RND2 Polyclonal Antibody

Catalog No.	Quantity
PIPA568319	100 μL

Catalog No. PIPA568319 Supplier Invitrogen™ Supplier No. PA568319

Description

Rabbit Polyclonal Antibody

Predicted to react with Mouse and Rat samples.

The Ras p21 family of guanine nucleotide proteins has been widely studied in view of its apparent role in signal transduction pathways and high frequency of mutations in human malignancies. It is now clear, however, that the Ras proteins (H-, K- and N-Ras p21) are members of a much larger superfamily of related proteins. Six members of this family, Rap 1A, Rap 1B, Rap 2, R-Ras, Ral A and Ral B, exhibit approximately 50% amino acid homology to Ras. The six mammalian Rho proteins (Rho A, B, C, G, 7 and 8) are approximately 30% homologous to Ras and are expressed in a wide range of cell types. Both Ras p21 and Rho p21, as well as other members of the Ras superfamily, contain a carboxy-terminal CAAX sequence (C, cysteine; A, aliphatic amino acid; X, any amino acid) which in the case of Ras has been shown to be essential for correct localization and function.

Specifications

• Antigen: RND2
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: RND2
• Gene Accession No.: P52198, Q9QYM5
• Gene Alias: aplysia ras-related homolog N (RhoN); ARHN; CTD-3199J23.4; GTP-binding protein Rho7; ras homolog gene family, member N; ras homolog N (RhoN); Rho family GTPase 2; RHO7; RhoN; Rho-related GTP-binding protein Rho7; rho-related GTP-binding protein RhoN; Rnd2; Rohn
• Gene Symbols: RND2
• Host Species: Rabbit
• Immunogen: Synthesized peptide derived from human RND2.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11858, 303553, 8153
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG