RNF139 Rabbit anti-Human, Polyclonal, Bioss 

Rabbit Polyclonal Antibody

Manufacturer:  Bioss BS6096R

Catalog No. 50-198-7041

Description

The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a ttranslocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.

Specifications

• Antigen: RNF139
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Gene: RNF139
• Format: Liquid
• Host Species: Rabbit
• Isotype: IgG
• Quantity: 100 μL
• Storage Requirements: -20°C
• Primary or Secondary: Primary
• Gene ID (Entrez): 11236

• Gene Symbol: RNF139
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: Q8WU17
• Gene Alias: 4930555P18Rik; E3 ubiquitin-protein ligase RNF139; HRCA1; MGC31961; multiple membrane spanning receptor TRC8; patched related protein translocated in renal cancer; RCA1; RING finger protein 139; RING-type E3 ubiquitin transferase RNF139; Rnf139; Translocation in renal carcinoma on chromosome 8 protein; TRC8
• Immunogen: KLH conjugated synthetic peptide derived from human RNF139.
• Purification Method: Protein A
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human