RNF14 Monoclonal Antibody (OTI3A4), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA810955

Catalog No. 50-168-3728

Description

The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A domit negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.

Specifications

• Antigen: RNF14
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q9UBS8
• Gene Symbols: RNF14
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-220 of human RNF14 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI3A4
• Conjugate: Unconjugated
• Gene: RNF14
• Gene Alias: ARA54, HFB30, HRIHFB2038, TRIAD2
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9604
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid