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RNF20 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. p-7209448 Shop All Proteintech Group Inc Products
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50-173-3519 150 μL
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Catalog No. 50-173-3519 Supplier Proteintech Group Inc Supplier No. 216251AP150UL
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Description

Rabbit Polyclonal Antibody

RNF20 is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. RNF20 selectively suppresses the expression of some genes such as several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS). In contrast, RNF20 also positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. Together with the deubiquitinase USP44, RNF20 regulates stem cell differentiation by modulating H2B monoubiquitination.

Specifications

Antigen RNF20
Applications Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RNF20
Gene Accession No. Q5DTM8, Q5VTR2
Gene Alias BRE1, BRE1 A, BRE1A, hBRE1, KIAA2779, ring finger protein 20, RNF20
Gene Symbols RNF20
Host Species Rabbit
Immunogen RNF20 Fusion Protein Ag16066
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 109331, 313216, 56254
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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