Invitrogen™ RNF43 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579930

Catalog No. PIPA579930

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human 293T whole cell, human COLO-320 whole cell, human SW620 whole cell, human MCF-7 whole cell.

E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.

Specifications

• Antigen: RNF43
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RNF43
• Gene Alias: 4732452J19Rik; E3 ubiquitin-protein ligase RNF43; RGD1305204; RING finger protein 43; RING-type E3 ubiquitin transferase RNF43; RNF124; Rnf43; URCC
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54894
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene Accession No.: Q68DV7
• Gene Symbols: RNF43
• Immunogen: E. coli-derived human RNF43 recombinant protein (Position: G24-Y197).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG