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Invitrogen™ RNF43 Polyclonal Antibody
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Catalog No. PIPA579930 Shop All Thermo Scientific Products
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100 μg
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PIPA579930 100 μg
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Catalog No. PIPA579930 Supplier Invitrogen™ Supplier No. PA579930
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human 293T whole cell, human COLO-320 whole cell, human SW620 whole cell, human MCF-7 whole cell.

E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RNF43
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose, 0.9mg NaCl, 0.2mg Na2PO4 and no preservative
Gene RNF43
Gene Accession No. Q68DV7
Gene Alias 4732452J19Rik; E3 ubiquitin-protein ligase RNF43; RGD1305204; RING finger protein 43; RING-type E3 ubiquitin transferase RNF43; RNF124; Rnf43; URCC
Gene Symbols RNF43
Host Species Rabbit
Immunogen E. coli-derived human RNF43 recombinant protein (Position: G24-Y197).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54894
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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