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  5. Tocris Bioscience™ Ro 25-6981 maleate

Tocris Bioscience™ Ro 25-6981 maleate
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Catalog No. 159410
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15-941-0 10 mg
15-945-0 50 mg
15-941-R 1 mg
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Catalog No. 15-941-0 Supplier Tocris Bioscience™ Supplier No. 1594/10
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Description

GluN2B-selective NMDA antagonist

Ro 25-6981 maleate is a potent and selective activity-dependent blocker of NMDA receptors containing the GluN2B (formally NR2B) subunit. IC50 values are 0.009 and 52 μM for cloned receptor subunit combinations GluN1C/GluN2B and GluN1C/GluN2A respectively. Displays neuroprotectant effects in vivo and in vitro.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Specifications

Chemical Name or Material (αR,βS)-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate
CAS 1312991-76-6
Assay Percent Range >98%
Quantity 10 mg
Solubility Soluble to 100mM in DMSO
Molecular Formula C22H29NO2.C4H4O4
Formula Weight Observed MW: 455.55

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