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Roquin Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501557804
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Catalog No. Quantity
50-155-7804 20 μL
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Catalog No. 50-155-7804 Supplier Bethyl Laboratories, Inc Supplier No. A300514AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

The ring finger protein RC3H1, also known as Roquin, is a highly conserved member of the RING type ubiquitin ligase protein family whose M199R mutation leads to the excessive production of follicular helper T cells and germinal centers in the sanroque strain of mice, a strain with excessive IL-21 production and high titers of autoantibodies. The complete loss of RC3H1 induces early death and immune deregulation but not autoimmunity in RC3H1-null mice, suggesting that the mutant RC3H1 is more disruptive to the immune system than its complete loss.

Specifications

Antigen Roquin
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene RC3H1
Gene Accession No. Q4VGL6, Q5TC82
Gene Alias RC3H1, Ring finger and CCCH-type domains 1, ring finger protein 198, RNF198, roquin
Gene Symbols RC3H1
Host Species Rabbit
Immunogen Between 500 and 550
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 149041, 381305
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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