Invitrogen™ RORB Monoclonal Antibody (OTI1G1)

Catalog No.	Quantity
PIMA526826	100 μL

Catalog No. PIMA526826

Supplier: Invitrogen™ MA526826

Description

Mouse Monoclonal Antibody

RORB Monoclonal Antibody for Western Blot, IHC (P)

Retinoid-related orphan receptor beta (ROR beta), a NR1 thyroid hormone receptor, affects the development and functioning of the central nervous system, including sensory input integration and circadian timing. Disruption of ROR beta in mice results in juvenile ataxia, retinal degeneration, circadian activity abnormalities, and delayed onset of male fertility. ROR beta binds to the monomeric response elements containing the sequence AnnTAGGTCA as a monomer. An alternatively spliced isoform, ROR beta2, has been isolated from rats, and the expression of ROR beta2 is confined to the pineal gland and retina. ROR beta2 shares common DNA- and putative ligand-binding domains with wild-type ROR beta but is characterized by a different amino-terminal domain. ROR beta expression has been documented in various regions of the mouse brain.

Specifications

• Antigen: RORB
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: OTI1G1
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: RORB
• Gene Accession No.: Q92753
• Gene Alias: bA133M9.1; Nr1f2; Nuclear receptor ROR-beta; nuclear receptor RZR-beta; Nuclear receptor subfamily 1 group F member 2; RAR related orphan receptor B; RAR-related orphan receptor B; RAR-related orphan receptor beta; retinoic acid-binding receptor beta; retinoid-related orphan receptor b; retinoid-related orphan receptor beta; retinoid-related orphan receptor-beta; ror beta; Rorb; Rorbeta; ROR-BETA; rzrb; RZR-beta; sb:eu943; transcription factor; Unknown (protein for IMAGE:7173671)
• Gene Symbols: RORB
• Host Species: Mouse
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-260 of RORB produced in E.coli.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6096
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1