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Tocris Bioscience™ Rotenone
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Catalog No. 361650
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Quantity:
50 mg
Catalog No. Quantity
36-165-0 50 mg
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Catalog No. 36-165-0

Supplier: Tocris Bioscience™ 3616/50

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Description

Inhibits complex I of the mitochondrial electron transport chain

Mitochondrial electron transport chain inhibitor (IC50 = 1.7 - 2.2 μM at complex I). Inhibits NADH oxidation by cardiac sarcoplasmic reticulum (IC50 = 3.4 nM). Commonly used pesticide and induces Parkinsonism in animal models. May also inhibit autophagy induction; blocks lysosomal degradation of autophagic vacuoles. Cell-permeable and brain penetrant.

Chemical Identifiers

CAS 83-79-4
Molecular Formula C23H22O6

Specifications

Quantity 50 mg
Formula Weight 394.42
Purity >95%
Molecular Weight (g/mol) 394.423
Chemical Name or Material Rotenone

Safety and Handling

Recommended Storage Store at Room Temperature
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