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RPE65 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501731888 Shop All Proteintech Group Inc Products
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50-173-1888 150 μL
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Catalog No. 50-173-1888 Supplier Proteintech Group Inc Supplier No. 179391AP150UL
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Description

Rabbit Polyclonal Antibody

RPE65 is a major protein of the retinal pigment epithelium (RPE). RPE65 is essential for the regeneration of rhodopsin in the visual cycle. Mutations in RPE65 are responsible for certain forms of autosomal recessive severe retinal dystrophy, including Leber Congenital Amaurosis (LCA). Loss of function results in a block in retinoid processing required for the synthesis of 11-cis retinal and the accumulation of retinyl esters in the RPE.

Specifications

Antigen RPE65
Applications Western Blot
Classification Polyclonal
Concentration 0.19 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene RPE65
Gene Accession No. O70276, Q16518, Q91ZQ5
Gene Alias LCA2, mRPE65, rd12, Retinoid isomerohydrolase, Retinol isomerase, RP20, RPE65, sRPE65
Gene Symbols RPE65
Host Species Rabbit
Immunogen RPE65 Fusion Protein Ag12356
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19892, 6121, 89826
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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