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Invitrogen™ RPRD1B Monoclonal Antibody (01)
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Catalog No. PIMA529525
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100 μL
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PIMA529525 100 μL
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Catalog No. PIMA529525 Supplier Invitrogen™ Supplier No. MA529525
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Description

Mouse Monoclonal Antibody

This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human RPRD1B.

Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD by RPAP2. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen RPRD1B
Applications Western Blot
Classification Monoclonal
Clone 01
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene RPRD1B
Gene Accession No. Q9NQG5
Gene Alias 2610304G08Rik; 2810446G03Rik; C20orf77; Cell cycle-related and expression-elevated protein in tumor; cell-cycle related and expression-elevated protein in tumor; CREPT; dJ1057B20.2; NET60; regulation of nuclear pre-mRNA domain containing 1B; regulation of nuclear pre-mRNA domain-containing protein 1B; RGD1304782; Rprd1b
Gene Symbols RPRD1B
Host Species Mouse
Immunogen Recombinant Human RPRD1B Protein (Met1-Asp326).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 58490
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2b
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