Invitrogen™ RPS17 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595760

Catalog No. PIPA595760

Description

Immunogen sequence: MGRVRTKTVK KAARVIIEKY YTRLGNDFHT NKRVCEEIAI IPSKKLRNKI AGYVTHLMKR IQRGPVRGIS IKLQEEERER RDNYVPEVSA LDQEIIEVDP; Positive Samples: 293T, A-549, DU145, BxPC-3, NIH/3T3, mouse brain.

Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein S17, also known as RPS17, RPS17L1 or RPS17L2, is a 135 amino acid protein that is a component of the 40S subunit. Localized to the cytoplasm and expressed ubiquitously, Ribosomal Protein S17 belongs to the S17e family of ribosomal proteins and functions in protein synthesis. Mutations in the gene encoding Ribosomal Protein S17 are associated with Diamond-Blackfan anemia (DBA), a rare congenital disorder characterized by defective differentiation of pro-erythroblasts. Like most ribosomal proteins, Ribosomal Protein S17 exists as multiple processed pseudogenes that are scattered throughout the genome.

Specifications

• Antigen: RPS17
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Rps17
• Gene Alias: 40S ribosomal protein S17; DBA4; ribosomal protein S17; Rps17; RPS17L; RPS17L1; RPS17L2; S17; Small ribosomal subunit protein eS17
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20068, 29286, 6218
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.17 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: P04644, P08708, P63276
• Gene Symbols: Rps17
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human RPS17 (NP_0010121).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov