RSAD2 Mouse anti-Human, Clone: OTI4D12, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF505799

Catalog No. 50-166-3924

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Viperin is a 43kDa protein which is one of several hundred interferon inducible viral proteins. Elevated expression of viperin is induced by LPS and poly I:C through TLR dependent signaling pathways. Sendai virus mediated viperin expression is induced independently of TLR signaling pathways through RLRs - RIG-I and MAVs (Severa, 2006). Viperin has been shown to play an important role in interferon mediated anti-viral activity in a Hepatitis C virus model system (Helbig, 2011). Viperin is induced in lymphoid cells and dendritic cells (DCs) and highly induced in neutrophils and macrophages during acute LCMV infection in mice (Hinson, ). Viperin functions as a mediator of viral resistance and as a marker for interferon responsiveness making its detection and mechanism of action through specific antibody probes valuable for further studies.

Specifications

• Antigen: RSAD2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: RSAD2
• Gene Alias: 2510004L01Rik, cig33, cig5, vig1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 91543
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Clone: OTI4D12
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q8WXG1
• Gene Symbols: RSAD2
• Immunogen: Full length human recombit protein of human RSAD2 produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b