Invitrogen™ RSV Fusion Protein Monoclonal Antibody (RSV3216)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA180661

Catalog No. PIMA180661

Description

Suitable as capture reagent with MA1-80039 as detection reagent in sandwich ELISA. Purity is >90% IgG. Mouse anti respiratory syncytial virus fusion protein antibody, clone RSV3216 recognizes an epitope within the RSV fusion protein (46 kDa and 22 kDa s-s linked glycoprotein).

Human respiratory syncytial virus (RSV) is a member of the Paramyxoviridae family, subfamily Pneumovirinae, that causes common respiratory tract infections such as measles and mumps. Its genome consists of single stranded, negative sense RNA that encodes three envelope glycoproteins, a small hydrophobic (SH) protein of unknown function, a major glycoprotein (G) known as the attachment protein, and a fusion (F) protein. The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, resulting in viral penetration, and can direct fusion of infected cells with adjoining cells, resulting in the formation of syncytia or multi nucleated giant cells. Its name comes from the fact that F proteins on the surface of the virus cause the membranes on nearby cells to merge, forming syncytia. While RSV typically produces mild symptoms in adults, it is one of the leading causes of lower respiratory tract infections and hospital visits during infancy and childhood.

Specifications

• Antigen: RSV Fusion Protein
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with <0.1% sodium azide; pH 7.5
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG2b

• Applications: ELISA, Flow Cytometry, Immunomicroscopy, Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: RSV3216
• Conjugate: Unconjugated
• Gene Alias: human respiratory syncytial virus; RSV; RSV Fusion protein; Rsvgp08
• Immunogen: Bovine RSV strains: 127, SNK and 9007. Human RSV strains: Long, Randall, 8/60, and A/2.
• Quantity: 1 mg
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

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