Invitrogen™ RTN4RL2 Recombinant Rabbit Monoclonal Antibody (P14)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA547936

Catalog No. PIMA547936

Description

Specificity: The antibody binds to human NgR2 with a Kd of 2.3 nM and to rat NgR2 with a Kd of 0.48 nM (bivalent binding).

Reticulon 4 receptor-like 2 (RTN4RL2), also known as NgR2and NgRH1, is a 60 kDa glycosylphosphatidylinositol-anchored protein that is expressed primarily in the brain. It contains eight leucine-rich repeats that are flanked by cysteine-rich sequences at both the N- and C-termini. The membrane anchored RTN4RL2 can be solubilized through the action of phospholipase or an unidentified MTMMP to generate a 46 kDa soluble receptor. It has been suggested that RTN4RL2 may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.

Specifications

• Antigen: RTN4RL2
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Gene Accession No.: Q7M6Z0, Q80WD1, Q86UN3
• Gene Symbols: RTN4RL2
• Immunogen: (His)6-tagged fragment of rat NgR2 (amino acids 279-420).
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG κ

• Applications: ELISA, Flow Cytometry, Immunoprecipitation, Western Blot
• Clone: P14
• Conjugate: Unconjugated
• Gene: RTN4RL2
• Gene Alias: ngR2; NGRH1; NGRL3; Nogo receptor-like 3; Nogo-66 receptor homolog 1; Nogo-66 receptor-related protein 2; reticulon 4 receptor-like 2; reticulon-4 receptor-like 2; RGD:727797}; Rtn4rl2; rtn4rl2 {ECO:0000312
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 269295, 311169, 349667
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid