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Invitrogen™ RUNX3 Polyclonal Antibody
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Catalog No. PIPA5102042
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PIPA5102042 100 μL
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Catalog No. PIPA5102042 Supplier Invitrogen™ Supplier No. PA5102042
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RUNX3.

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RUNX3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RUNX3
Gene Accession No. Q13761
Gene Alias Acute myeloid leukemia 2 protein; acute myeloid leukemia gene 2; AML2; CBFA3; CBF-alpha 3; CBF-alpha-3; core binding factor alpha 3; core-binding factor subunit alpha-3; core-binding factor, runt domain, alpha subunit 3; oncogene AML-2; PEA2 alpha C; PEA2-alpha C; PEBP2 alpha C; PEBP2A3; PEBP2aC; PEBP2-alpha C; polyomavirus enhancer-binding protein 2 alpha C subunit; runt domain, alpha subunit 3; Runt related transcription factor 3; runt-related transcription factor 3; RUNX3; SL3/AKV core-binding factor alpha C subunit; SL3-3 enhancer factor 1 alpha C subunit; transcription factor AML2; transcription factor AML2/CBFA3
Gene Symbols RUNX3
Host Species Rabbit
Immunogen A synthesized peptide derived from human RUNX3(Accession Q13761), corresponding to amino acid residues V163-P213.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 864
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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