Invitrogen™ Ruplizumab Recombinant Human Monoclonal Antibody (hu5c8 (Ruplizumab))

Catalog No.	Quantity
PIMA547965	200 μg

Catalog No. PIMA547965

Supplier: Invitrogen™ MA547965

Description

Human Recombinant Monoclonal Antibody

Specificity: The antibody binds to CD40L with an IC50 of 0.845 μg/mL.

Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive pharmaceutical and is a component of Antova. Ruplizumab is an anti-CD40L monoclonal antibody. The binding of CD40 to its ligand, CD40L is a critical element in T cell activation. In systemic lupus erythematosus, CD40L is over-expressed on T cells, B cells and monocytes.

Specifications

• Antigen: Ruplizumab
• Applications: Flow Cytometry, Inhibition Assays, Western Blot
• Classification: Recombinant Monoclonal
• Clone: hu5c8 (Ruplizumab)
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.02% ProClin 300
• Gene: Ntrk1
• Gene Accession No.: P04629
• Gene Alias: BG-9588; hu5c8
• Host Species: Human
• Immunogen: Human CD40L.
• Purification Method: Protein A
• Quantity: 200 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4914
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1 κ