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Invitrogen™ Ruplizumab Recombinant Human Monoclonal Antibody (hu5c8 (Ruplizumab))
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Catalog No. PIMA547965
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200 μg
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Catalog No. Quantity
PIMA547965 200 μg
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Catalog No. PIMA547965 Supplier Invitrogen™ Supplier No. MA547965
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Description

Human Recombinant Monoclonal Antibody

Specificity: The antibody binds to CD40L with an IC50 of 0.845 μg/mL.

Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive pharmaceutical and is a component of Antova. Ruplizumab is an anti-CD40L monoclonal antibody. The binding of CD40 to its ligand, CD40L is a critical element in T cell activation. In systemic lupus erythematosus, CD40L is over-expressed on T cells, B cells and monocytes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Ruplizumab
Applications Flow Cytometry, Inhibition Assays, Western Blot
Classification Recombinant Monoclonal
Clone hu5c8 (Ruplizumab)
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene Ntrk1
Gene Accession No. P04629
Gene Alias BG-9588; hu5c8
Host Species Human
Immunogen Human CD40L.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4914
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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