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Tocris Bioscience™ RVG29-Cys

Catalog No. 89035
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5 mg
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89-035 5 mg
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Catalog No. 89-035 Supplier Tocris Bioscience™ Supplier No. 8903/5
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Description

Nicotinic acetylcholine receptor targeting peptide for neuronal delivery

RVG29-Cys is a peptide derived from rabies virus glycoprotein (RVG) able to specifically bind on the nicotinic acetylcholine receptors (nAchR) present on neuronal cells. RVG29-Cys can be used to functionalize LNPs via thiol-maleimide click chemistry for targeting nAchR present on blood-brain barrier (BBB). mRNA LNPs functionalized with RVG29-Cys shows improved transfection efficiency in cultured brain endothelial and neuronal cells, and in vivo, after systemic administration in mice.

Specifications

Purity 95%
CAS 1404289-25-3
Content And Storage Store at -20°C
Molecular Weight (g/mol) Observed: 3369.79
Quantity 5 mg
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