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Invitrogen™ RXRA Recombinant Rabbit Monoclonal Antibody (K01_1X76)
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Catalog No. MA563451
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MA564910 50 μL
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Catalog No. MA563451 Supplier Invitrogen™ Supplier No. MA563451
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Rabbit Recombinant Monoclonal Antibody

RXRA Recombinant Monoclonal Antibody for ICC/IF, Western Blot

Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma), preferentially bind 9-cis -RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.
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Specifications

Antigen RXRA
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone K01_1X76
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 0.05% BSA, 150mM NaCl, 40% glycerol and 0.01% sodium azide; pH 7.4
Gene Rxra
Gene Accession No. P19793, Q05343
Gene Alias 9530071D11Rik; Nr2b1; Nuclear receptor subfamily 2 group B member 1; retinoic acid receptor RXR-alpha; retinoid X nuclear receptor alpha; retinoid X receptor; retinoid X receptor alpha; retinoid X receptor, alpha; rxr alpha; RXR alpha 1; Rxra; RXRalpha1
Gene Symbols Rxra
Host Species Rabbit
Immunogen A synthetic peptide of human Retinoid X Receptor alpha.
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25271, 6256
Target Species Human, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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