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Invitrogen™ S100B Monoclonal Antibody (4C4.9)
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Catalog No. PIMA512969
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500 μL
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Catalog No. Quantity
PIMA512969 500 μL
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Catalog No. PIMA512969 Supplier Invitrogen™ Supplier No. MA512969
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Description

Mouse Monoclonal Antibody

MA5-12969 targets S100 Protein in IHC (P), ICC/IF and WB applications and shows reactivity with Bovine, Human, mouse, and Rat samples. The MA5-12969 immunogen is purified bovine brain S100 protein.

S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen S100B
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 4C4.9
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene S100B
Gene Accession No. P02638, P04271, P50114
Gene Alias AI850290; Bpb; hypothetical protein LOC525716; NEF; protein S100-B; S100; S100 calcium binding protein B; S100 calcium binding protein beta (neural); S100 calcium-binding protein B; S100 calcium-binding protein beta (neural); S-100 calcium-binding protein beta subunit; S100 calcium-binding protein, beta (neural); S-100 calcium-binding protein, beta chain; S100 protein beta chain; S-100 protein beta chain; S-100 protein subunit beta; S100 protein, beta polypeptide; S100 protein, beta polypeptide, neural; S100B; S100-B; S100beta; S100P
Gene Symbols S100B
Host Species Mouse
Immunogen Purified bovine brain S100 protein.
Purification Method Protein A/G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20203, 525716, 6285
Target Species Bovine, Human, Mouse
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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