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S100A10 Mouse anti-Human, Clone: 1B3F9, Proteintech
SDP

Catalog No. p-7213108 Shop All Proteintech Group Inc Products
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50-173-6660 150 μL
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Catalog No. 50-173-6660 Supplier Proteintech Group Inc Supplier No. 662271IG150UL
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Description

Mouse Monoclonal Antibody

The S-100 family of calcium-activated proteins interact with a range of target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II, though this association is not required for plasma membrane localization or binding and activation of plasminogen. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B (Hep B) virus polymerase. Hep B virus polymerase normally localizes to the cytoplasm only, though in the presence of S-100A10 a portion relocates to the nucleus, implying a role for S-100A10 and intracellular calcium in the process of viral replication.

Specifications

Antigen S100A10
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1B3F9
Concentration 1.72 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene S100A10
Gene Accession No. P60903
Gene Alias 42C, ANX2L, ANX2LG, Ca[1], CAL1L, Calpactin 1 light chain, Calpactin I light chain, Cellular ligand of annexin II, CLP11, GP11, p10, p10 protein, P11, Protein S100 A10, S100A10
Gene Symbols S100A10
Host Species Mouse
Immunogen S100A10 Fusion Protein Ag23596
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6281
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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