Invitrogen™ S100B Monoclonal Antibody (SH-B4)

Catalog No.	Quantity
MA125005	100 μL

Catalog No. MA125005 Supplier Invitrogen™ Supplier No. MA125005

Description

Mouse Monoclonal Antibody

Recommended positive controls: human tongue. MA1-25005 has a predicted molecular weight of 10.5 kDa. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

Specifications

• Antigen: S100B
• Applications: ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: SH-B4
• Concentration: 3.8 mg/mL
• Conjugate: Unconjugated
• Formulation: Ascites with 15mM sodium azide
• Gene: S100B
• Gene Accession No.: P02638, P04271, P04631, P50114, Q6YNR6
• Gene Alias: AI850290; Bpb; hypothetical protein LOC525716; NEF; protein S100-B; S100; S100 calcium binding protein B; S100 calcium binding protein beta (neural); S100 calcium-binding protein B; S100 calcium-binding protein beta (neural); S-100 calcium-binding protein beta subunit; S100 calcium-binding protein, beta (neural); S-100 calcium-binding protein, beta chain; S100 protein beta chain; S-100 protein beta chain; S-100 protein subunit beta; S100 protein, beta polypeptide; S100 protein, beta polypeptide, neural; S100B; S100-B; S100beta; S100P
• Gene Symbols: S100B
• Host Species: Mouse
• Immunogen: Bovine brain S-100b.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 100009495, 100623510, 101099488, 101113190, 102169524, 20203, 25742, 491615, 525716, 6285
• Target Species: Human, Mouse, Rat, Canine, Rabbit, Bovine, Sheep, Pig, Feline, Goat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1